0000001 - Document - Cover link:presentationLink link:calculationLink link:definitionLink 9952151 - Statement - CONDENSED CONSOLIDATED BALANCE SHEETS (Unaudited) link:presentationLink link:calculationLink link:definitionLink 9952152 - Statement - CONDENSED CONSOLIDATED BALANCE SHEETS (Unaudited) (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 9952153 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (Unaudited) link:presentationLink link:calculationLink link:definitionLink 9952154 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE LOSS (Unaudited) link:presentationLink link:calculationLink link:definitionLink 9952155 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF CHANGES IN STOCKHOLDERS' EQUITY (Unaudited) link:presentationLink link:calculationLink link:definitionLink 9952156 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (Unaudited) link:presentationLink link:calculationLink link:definitionLink 9952157 - Disclosure - Business Organization and Presentation link:presentationLink link:calculationLink link:definitionLink 9952158 - Disclosure - Summary of Significant Accounting Policies link:presentationLink link:calculationLink link:definitionLink 9952159 - Disclosure - Marketable Securities link:presentationLink link:calculationLink link:definitionLink 9952160 - Disclosure - Fair Value Measurements link:presentationLink link:calculationLink link:definitionLink 9952161 - Disclosure - Inventory link:presentationLink link:calculationLink link:definitionLink 9952162 - Disclosure - Intangible Assets link:presentationLink link:calculationLink link:definitionLink 9952163 - Disclosure - Accounts Payable and Accrued Liabilities link:presentationLink link:calculationLink link:definitionLink 9952164 - Disclosure - Commitments and Contingencies link:presentationLink link:calculationLink link:definitionLink 9952165 - Disclosure - Accumulated Other Comprehensive Income link:presentationLink link:calculationLink link:definitionLink 9952166 - Disclosure - Stock-Based Compensation link:presentationLink link:calculationLink link:definitionLink 9952167 - Disclosure - Income Taxes link:presentationLink link:calculationLink link:definitionLink 9952168 - Disclosure - Earnings per Share link:presentationLink link:calculationLink link:definitionLink 9952169 - Disclosure - Segments link:presentationLink link:calculationLink link:definitionLink 9952170 - Disclosure - Legal Matters link:presentationLink link:calculationLink link:definitionLink 9955511 - Disclosure - Summary of Significant Accounting Policies (Policies) link:presentationLink link:calculationLink link:definitionLink 9955512 - Disclosure - Summary of Significant Accounting Policies (Tables) link:presentationLink link:calculationLink link:definitionLink 9955513 - Disclosure - Marketable Securities (Tables) link:presentationLink link:calculationLink link:definitionLink 9955514 - Disclosure - Fair Value Measurements (Tables) link:presentationLink link:calculationLink link:definitionLink 9955515 - Disclosure - Inventory (Tables) link:presentationLink link:calculationLink link:definitionLink 9955516 - Disclosure - Intangible Assets (Tables) link:presentationLink link:calculationLink link:definitionLink 9955517 - Disclosure - Accounts Payable and Accrued Liabilities (Tables) link:presentationLink link:calculationLink link:definitionLink 9955518 - Disclosure - Accumulated Other Comprehensive Income (Tables) link:presentationLink link:calculationLink link:definitionLink 9955519 - Disclosure - Stock-Based Compensation (Tables) link:presentationLink link:calculationLink link:definitionLink 9955520 - Disclosure - Earnings per Share (Tables) link:presentationLink link:calculationLink link:definitionLink 9955521 - Disclosure - Segments (Tables) link:presentationLink link:calculationLink link:definitionLink 9955522 - Disclosure - Business Organization and Presentation (Details) link:presentationLink link:calculationLink link:definitionLink 9955523 - Disclosure - Summary of Significant Accounting Policies - Schedule of Reconciliation of Cash, Cash Equivalents and Restricted Cash (Details) link:presentationLink link:calculationLink link:definitionLink 9955524 - Disclosure - Summary of Significant Accounting Policies - Schedule of Net Product Sales (Details) link:presentationLink link:calculationLink link:definitionLink 9955525 - Disclosure - Summary of Significant Accounting Policies - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955526 - Disclosure - Marketable Securities (Details) link:presentationLink link:calculationLink link:definitionLink 9955527 - Disclosure - Fair Value Measurements - Schedule of Assets Measured at Fair Value on Recurring Basis (Details) link:presentationLink link:calculationLink link:definitionLink 9955528 - Disclosure - Fair Value Measurements - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955529 - Disclosure - Inventory - Schedule of Inventory (Details) link:presentationLink link:calculationLink link:definitionLink 9955530 - Disclosure - Inventory - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955531 - Disclosure - Intangible Assets - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955532 - Disclosure - Intangible Assets - Schedule of Intangible Assets (Details) link:presentationLink link:calculationLink link:definitionLink 9955533 - Disclosure - Intangible Assets - Schedule of Future Intangible Asset Amortization (Details) link:presentationLink link:calculationLink link:definitionLink 9955534 - Disclosure - Accounts Payable and Accrued Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955535 - Disclosure - Commitments and Contingencies - Fanapt - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955536 - Disclosure - Commitments and Contingencies - HETLIOZ - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955537 - Disclosure - Commitments and Contingencies - NEREUS - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955538 - Disclosure - Commitments and Contingencies - Imsidolimab - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955539 - Disclosure - Commitments and Contingencies - Portfolio of CFTR Activators and Inhibitors - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955540 - Disclosure - Commitments and Contingencies - VQW-765 - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955541 - Disclosure - Commitments and Contingencies - Other Agreements - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955542 - Disclosure - Commitments and Contingencies - Purchase Commitments - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955543 - Disclosure - Accumulated Other Comprehensive Income (Details) link:presentationLink link:calculationLink link:definitionLink 9955544 - Disclosure - Stock-Based Compensation - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955545 - Disclosure - Stock-Based Compensation - Stock Option - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955546 - Disclosure - Stock-Based Compensation - Schedule of Option Activity (Details) link:presentationLink link:calculationLink link:definitionLink 9955547 - Disclosure - Stock-Based Compensation - Restricted Stock Units - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955548 - Disclosure - Stock-Based Compensation - Schedule of RSU Activity (Details) link:presentationLink link:calculationLink link:definitionLink 9955549 - Disclosure - Stock-Based Compensation - Performance Restricted Stock Units - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955550 - Disclosure - Stock-Based Compensation - Schedule of PSU Activity (Details) link:presentationLink link:calculationLink link:definitionLink 9955551 - Disclosure - Stock-Based Compensation - Schedule of Stock-Based Compensation Expense (Details) link:presentationLink link:calculationLink link:definitionLink 9955552 - Disclosure - Stock-Based Compensation - Stock-Based Compensation Expense - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955553 - Disclosure - Stock-Based Compensation - Schedule of Mote Carlo Model for PSUs Granted (Details) link:presentationLink link:calculationLink link:definitionLink 9955554 - Disclosure - Income Taxes (Details) link:presentationLink link:calculationLink link:definitionLink 9955555 - Disclosure - Earnings per Share (Details) link:presentationLink link:calculationLink link:definitionLink 9955556 - Disclosure - Segments - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955557 - Disclosure - Segments - Schedule of Segment Revenue and Significant Expenses (Details) link:presentationLink link:calculationLink link:definitionLink